The half-day workshop is focused on the methodology and applications of novel sampling and fast pulsing techniques in NMR of biomolecules. A distinct feature of NMR spectroscopy, the possibility to simultaneously observe hundreds of atoms in complex macromolecules, comes with a significant price tag. The ultimate resolution obtained in multidimensional experiments requires the long data collection times needed to systematically sample the large multidimensional spectral space. The number of measured data points increases polynomially with the spectrometer field and the desired spectral resolution, and exponentially with the number of dimensions. The problem of lengthy sampling compromises or even prohibits many applications of multidimensional spectroscopy in chemistry and molecular biology. Fortunately, the advent of “fast” NMR spectroscopy offers a number of solutions.
The venue is the Swedish NMR Centre, Medicinaregatan 5C, Gothenburg. The workshop is free of charge for a maximum number of 20 registered participants (including coffee and sandwich).
Sponsors: Swedish NMR Center at the University of Gothenburg
Organizers: Vladislav Orekhov, Martin Billeter
Register with the form below.
Wednesday Nov 21, 2012
10.15 - 10.30 Coffee
10.30 – 11.00 K. Kazimierczuk, University of Warsaw, Poland “Compressed sensing in NMR spectroscopy”
11.00 – 11.30 M. Billeter, University of Gothenburg, Sweden “Structural characterization of proteins by projection-decomposition”
11.30 – 12.10 S. Hyberts, Harvard Medical School, USA “Details of Sampling Strategy - Sensitivity Gain Possible?”
12.10 – 13.30 Free lunch sandwich for registered participants
13.30 – 14.10 B. Brutscher, Inst. de Biologie Structurale, France “Fast-Pulsing NMR Techniques: Applications to the Study of Protein Folding and Structural Disorder”
14.10 – 14.40 V. Orekhov, University of Gothenburg, Sweden, “New tools for studying Intrinsically Disordered proteins“